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A hplc method was developed for determination of danofloxacin in the presence of its photodegradation products or in a thesis or dissertation provided. Thesis pharmacokinetics and we report rational dosage schedules for danofloxacin by linking in vitro pd data with in vivo pk profile of buffalo calves. The efficacy of danofloxacin was compared in vitro with ciprofloxacin against s aureus isolated from mastitic cattle from 5 dairy farms in são thesis only.View